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When a meteor explodes over a snow-covered Russian industrial metropolis spreading a deadly virus that turns thousands of the city dwellers into the walking dead, Ramses Campbell--an African American martial arts instructor, and a rising HBO Sports star, who has come to Russia to teach seminars--must fight to survive. In this deathtrap of a city, Ramses joins a group of survivors of various nationalities: a Russian interpreter, an English hotel manager, a Serbian executive chef, a Swedish sex tourist, a German Catholic priest, a Turkish engineer, and a blind Chinese teenage girl. They barricade themselves in a hotel and desperately fight back against the attacks of bloodthirsty cannibals. But, it turns out that sometimes it is easier to fight the living dead than your neighbor from across the hallway.